Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains

Mitochondria play a key role in common neurodegenerative diseases and contain their own genome: mtDNA. Common inherited polymorphic variants of mtDNA have been associated with several neurodegenerative diseases, and somatic deletions of mtDNA have been found in affected brain regions. However, there...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Keogh, Michael J., Wilson, Ian, Coxhead, Jonathan, Ryan, Sarah, Rollinson, Sara, Griffin, Helen, Kurzawa-Akinibi, Marzena, Santibanez-Koref, Mauro, Talbot, Kevin, Turner, Martin R., McKenzie, Chris-Anne, Troakes, Claire, Attems, Johannes, Smith, Colin, Al Sarraj, Safa, Morris, Christopher M., Ansorge, Olaf, Pickering-Brown, Stuart, Ironside, James W., Chinnery, Patrick F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290662/
https://www.ncbi.nlm.nih.gov/pubmed/28153046
http://dx.doi.org/10.1186/s40478-016-0404-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290662/
https://www.ncbi.nlm.nih.gov/pubmed/28153046
http://dx.doi.org/10.1186/s40478-016-0404-6

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