Faithful SGCE imprinting in iPSC-derived cortical neurons: an endogenous cellular model of myoclonus-dystonia

In neuropathology research, induced pluripotent stem cell (iPSC)-derived neurons are considered a tool closely resembling the patient brain. Albeit in respect to epigenetics, this concept has been challenged. We generated iPSC-derived cortical neurons from myoclonus-dystonia patients with mutations...

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Detalles Bibliográficos
Autores principales: Grütz, Karen, Seibler, Philip, Weissbach, Anne, Lohmann, Katja, Carlisle, Francesca A., Blake, Derek J., Westenberger, Ana, Klein, Christine, Grünewald, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290732/
https://www.ncbi.nlm.nih.gov/pubmed/28155872
http://dx.doi.org/10.1038/srep41156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290732/
https://www.ncbi.nlm.nih.gov/pubmed/28155872
http://dx.doi.org/10.1038/srep41156

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