Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Activation of the kynurenine pathway (KP) of tryptophan metabolism results from chronic inflammation and is known to exacerbate progression of neurodegenerative disease. To gain insights into the links between inflammation, the KP and multiple sclerosis (MS) pathogenesis, we investigated the KP meta...

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Detalles Bibliográficos
Autores principales: Lim, Chai K., Bilgin, Ayse, Lovejoy, David B., Tan, Vanessa, Bustamante, Sonia, Taylor, Bruce V., Bessede, Alban, Brew, Bruce J., Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290739/
https://www.ncbi.nlm.nih.gov/pubmed/28155867
http://dx.doi.org/10.1038/srep41473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290739/
https://www.ncbi.nlm.nih.gov/pubmed/28155867
http://dx.doi.org/10.1038/srep41473

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