Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-(13)C]Dehydroascorbic Acid Reduction Using (13)C Magnetic Resonance Spectroscopy

Rapid cancer cell proliferation promotes the production of reducing equivalents, which counteract the effects of relatively high levels of reactive oxygen species. Reactive oxygen species levels increase in response to chemotherapy and cell death, whereas an increase in antioxidant capacity can conf...

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Detalles Bibliográficos
Autores principales: Timm, Kerstin N., Hu, De-En, Williams, Michael, Wright, Alan J., Kettunen, Mikko I., Kennedy, Brett W. C., Larkin, Timothy J., Dzien, Piotr, Marco-Rius, Irene, Bohndiek, Sarah E., Brindle, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290948/
https://www.ncbi.nlm.nih.gov/pubmed/27994059
http://dx.doi.org/10.1074/jbc.M116.761536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290948/
https://www.ncbi.nlm.nih.gov/pubmed/27994059
http://dx.doi.org/10.1074/jbc.M116.761536

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