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Serodiagnosis of Zika virus (ZIKV) infections by a novel NS1-based ELISA devoid of cross-reactivity with dengue virus antibodies: a multicohort study of assay performance, 2015 to 2016

Serological diagnosis of Zika virus (ZIKV) infections is challenging due to high cross-reactivity between flaviviruses. We evaluated the diagnostic performance of a novel anti-ZIKV ELISA based on recombinant ZIKV non-structural protein 1 (NS1). Assay sensitivity was examined using sera from 27 patie...

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Detalles Bibliográficos
Autores principales: Steinhagen, Katja, Probst, Christian, Radzimski, Christiane, Schmidt-Chanasit, Jonas, Emmerich, Petra, van Esbroeck, Marjan, Schinkel, Janke, Grobusch, Martin P, Goorhuis, Abraham, Warnecke, Jens M, Lattwein, Erik, Komorowski, Lars, Deerberg, Andrea, Saschenbrecker, Sandra, Stöcker, Winfried, Schlumberger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291135/
https://www.ncbi.nlm.nih.gov/pubmed/28006649
http://dx.doi.org/10.2807/1560-7917.ES.2016.21.50.30426