Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

[Image: see text] Targeting organelles by modulating the redox potential of mitochondria is a promising approach to kill cancer cells that minimizes acquired drug resistance. However, it lacks selectivity because mitochondria perform essential functions for (almost) all cells. We show that enzyme-in...

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Detalles Bibliográficos
Autores principales: Wang, Huaimin, Feng, Zhaoqianqi, Wang, Youzhi, Zhou, Rong, Yang, Zhimou, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291163/
https://www.ncbi.nlm.nih.gov/pubmed/27960313
http://dx.doi.org/10.1021/jacs.6b09783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291163/
https://www.ncbi.nlm.nih.gov/pubmed/27960313
http://dx.doi.org/10.1021/jacs.6b09783

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