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IL1B-CGTC haplotype is associated with colorectal cancer in admixed individuals with increased African ancestry

Single-nucleotide polymorphisms (SNPs) in cytokine genes can affect gene expression and thereby modulate inflammation and carcinogenesis. However, the data on the association between SNPs in the interleukin 1 beta gene (IL1B) and colorectal cancer (CRC) are conflicting. We found an association betwe...

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Detalles Bibliográficos
Autores principales: Sanabria-Salas, María Carolina, Hernández-Suárez, Gustavo, Umaña-Pérez, Adriana, Rawlik, Konrad, Tenesa, Albert, Serrano-López, Martha Lucía, Sánchez de Gómez, Myriam, Rojas, Martha Patricia, Bravo, Luis Eduardo, Albis, Rosario, Plata, José Luis, Green, Heather, Borgovan, Theodor, Li, Li, Majumdar, Sumana, Garai, Jone, Lee, Edward, Ashktorab, Hassan, Brim, Hassan, Margolin, David, Fejerman, Laura, Zabaleta, Jovanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291207/
https://www.ncbi.nlm.nih.gov/pubmed/28157220
http://dx.doi.org/10.1038/srep41920