Two p53 tetramers bind one consensus DNA response element

p53 tumor suppressor is a transcription factor that controls cell cycle and genetic integrity. In response to genotoxic stress p53 activates DNA repair, cell cycle arrest, apoptosis or senescence, which are initiated via p53 binding to its specific DNA response elements (RE). The consensus p53 DNA R...

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Detalles Bibliográficos
Autores principales: Kearns, Sinéad, Lurz, Rudi, Orlova, Elena V., Okorokov, Andrei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291249/
https://www.ncbi.nlm.nih.gov/pubmed/27034469
http://dx.doi.org/10.1093/nar/gkw215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291249/
https://www.ncbi.nlm.nih.gov/pubmed/27034469
http://dx.doi.org/10.1093/nar/gkw215

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