A 10S galectin-3–U1 snRNP complex assembles into active spliceosomes

In previous studies, we reported that fractionation of HeLa cell nuclear extracts on glycerol gradients revealed an endogenous ∼10S particle that contained galectin-3 and U1 snRNP and this particle was sufficient to load the galectin polypeptide onto a pre-mRNA substrate. We now document that this i...

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Detalles Bibliográficos
Autores principales: Haudek, Kevin C., Voss, Patricia G., Wang, John L., Patterson, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291251/
https://www.ncbi.nlm.nih.gov/pubmed/27105840
http://dx.doi.org/10.1093/nar/gkw303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291251/
https://www.ncbi.nlm.nih.gov/pubmed/27105840
http://dx.doi.org/10.1093/nar/gkw303

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