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Adenosine to Inosine editing frequency controlled by splicing efficiency

Alternative splicing and adenosine to inosine (A to I) RNA-editing are major factors leading to co- and post-transcriptional modification of genetic information. Both, A to I editing and splicing occur in the nucleus. As editing sites are frequently defined by exon–intron basepairing, mRNA splicing...

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Detalles Bibliográficos
Autores principales: Licht, Konstantin, Kapoor, Utkarsh, Mayrhofer, Elisa, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291252/
https://www.ncbi.nlm.nih.gov/pubmed/27112566
http://dx.doi.org/10.1093/nar/gkw325