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The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix

Precise conversion of genetic information into proteins is essential to cellular health. However, a margin of error exists and is at its highest on the stage of translation of mRNA by the ribosome. Here we present three crystal structures of 70S ribosome complexes with messenger RNA and transfer RNA...

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Detalles Bibliográficos
Autores principales: Rozov, Alexey, Westhof, Eric, Yusupov, Marat, Yusupova, Gulnara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291260/
https://www.ncbi.nlm.nih.gov/pubmed/27174928
http://dx.doi.org/10.1093/nar/gkw431