Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome

The long terminal repeat (LTR) of the proviral human immunodeficiency virus (HIV)-1 genome is integral to virus transcription and host cell infection. The guanine-rich U3 region within the LTR promoter, previously shown to form G-quadruplex structures, represents an attractive target to inhibit HIV...

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Detalles Bibliográficos
Autores principales: De Nicola, Beatrice, Lech, Christopher J., Heddi, Brahim, Regmi, Sagar, Frasson, Ilaria, Perrone, Rosalba, Richter, Sara N., Phan, Anh Tuân
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291261/
https://www.ncbi.nlm.nih.gov/pubmed/27298260
http://dx.doi.org/10.1093/nar/gkw432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291261/
https://www.ncbi.nlm.nih.gov/pubmed/27298260
http://dx.doi.org/10.1093/nar/gkw432

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