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Post-translational control of genetic circuits using Potyvirus proteases

Genetic engineering projects often require control over when a protein is degraded. To this end, we use a fusion between a degron and an inactivating peptide that can be added to the N-terminus of a protein. When the corresponding protease is expressed, it cleaves the peptide and the protein is degr...

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Detalles Bibliográficos
Autores principales: Fernandez-Rodriguez, Jesus, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291274/
https://www.ncbi.nlm.nih.gov/pubmed/27298256
http://dx.doi.org/10.1093/nar/gkw537