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Post-translational control of genetic circuits using Potyvirus proteases
Genetic engineering projects often require control over when a protein is degraded. To this end, we use a fusion between a degron and an inactivating peptide that can be added to the N-terminus of a protein. When the corresponding protease is expressed, it cleaves the peptide and the protein is degr...
Autores principales: | Fernandez-Rodriguez, Jesus, Voigt, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291274/ https://www.ncbi.nlm.nih.gov/pubmed/27298256 http://dx.doi.org/10.1093/nar/gkw537 |
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