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Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity

The cohesin complex plays an important role in sister chromatin cohesion. Cohesin's core is composed of two structural maintenance of chromosome (SMC) proteins, called Smc1 and Smc3. SMC proteins are built from a globular hinge domain, a rod-shaped domain composed of long anti-parallel coiled-c...

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Detalles Bibliográficos
Autores principales: Orgil, Ola, Mor, Hadar, Matityahu, Avi, Onn, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291275/
https://www.ncbi.nlm.nih.gov/pubmed/27307603
http://dx.doi.org/10.1093/nar/gkw539