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Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells

The activation of mast cells (MC) is part of the innate and adaptive immune responses and depends on Ca(2+) entry across the plasma membrane, leading to the release of preformed inflammatory mediators by degranulation or by de novo synthesis. The calcium conducting channels of the TRPV family, known...

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Detalles Bibliográficos
Autores principales: Solís-López, A., Kriebs, U., Marx, A., Mannebach, S., Liedtke, W. B., Caterina, M. J., Freichel, M., Tsvilovskyy, V. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291405/
https://www.ncbi.nlm.nih.gov/pubmed/28158279
http://dx.doi.org/10.1371/journal.pone.0171366