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Potential roles of DNA methylation in the initiation and establishment of replicative senescence revealed by array-based methylome and transcriptome analyses

Cellular senescence is classified into two groups: replicative and premature senescence. Gene expression and epigenetic changes are reported to differ between these two groups and cell types. Normal human diploid fibroblast TIG-3 cells have often been used in cellular senescence research; however, t...

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Detalles Bibliográficos
Autores principales: Sakaki, Mizuho, Ebihara, Yukiko, Okamura, Kohji, Nakabayashi, Kazuhiko, Igarashi, Arisa, Matsumoto, Kenji, Hata, Kenichiro, Kobayashi, Yoshiro, Maehara, Kayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291461/
https://www.ncbi.nlm.nih.gov/pubmed/28158250
http://dx.doi.org/10.1371/journal.pone.0171431