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Potential roles of DNA methylation in the initiation and establishment of replicative senescence revealed by array-based methylome and transcriptome analyses
Cellular senescence is classified into two groups: replicative and premature senescence. Gene expression and epigenetic changes are reported to differ between these two groups and cell types. Normal human diploid fibroblast TIG-3 cells have often been used in cellular senescence research; however, t...
Autores principales: | Sakaki, Mizuho, Ebihara, Yukiko, Okamura, Kohji, Nakabayashi, Kazuhiko, Igarashi, Arisa, Matsumoto, Kenji, Hata, Kenichiro, Kobayashi, Yoshiro, Maehara, Kayoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291461/ https://www.ncbi.nlm.nih.gov/pubmed/28158250 http://dx.doi.org/10.1371/journal.pone.0171431 |
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