A combined approach of hollow microneedles and nanocarriers for skin immunization with plasmid DNA encoding ovalbumin

The aim of this study was to investigate the use of different types of microneedles (MNs) and nanocarriers for in vitro skin permeation and in vivo immunization of plasmid DNA encoding ovalbumin (pOVA). In vitro skin permeation studies indicated that hollow MNs had a superior enhancing effect on ski...

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Detalles Bibliográficos
Autores principales: Pamornpathomkul, Boonnada, Wongkajornsilp, Adisak, Laiwattanapaisal, Wanida, Rojanarata, Theerasak, Opanasopit, Praneet, Ngawhirunpat, Tanasait
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291464/
https://www.ncbi.nlm.nih.gov/pubmed/28184159
http://dx.doi.org/10.2147/IJN.S125945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291464/
https://www.ncbi.nlm.nih.gov/pubmed/28184159
http://dx.doi.org/10.2147/IJN.S125945

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