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A combined approach of hollow microneedles and nanocarriers for skin immunization with plasmid DNA encoding ovalbumin
The aim of this study was to investigate the use of different types of microneedles (MNs) and nanocarriers for in vitro skin permeation and in vivo immunization of plasmid DNA encoding ovalbumin (pOVA). In vitro skin permeation studies indicated that hollow MNs had a superior enhancing effect on ski...
Autores principales: | Pamornpathomkul, Boonnada, Wongkajornsilp, Adisak, Laiwattanapaisal, Wanida, Rojanarata, Theerasak, Opanasopit, Praneet, Ngawhirunpat, Tanasait |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291464/ https://www.ncbi.nlm.nih.gov/pubmed/28184159 http://dx.doi.org/10.2147/IJN.S125945 |
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