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Protein kinase C theta is required for efficient induction of IL-10-secreting T cells
Secretion of interleukin-10 (IL-10) by CD4(+) T cells is an essential immunoregulatory mechanism. The work presented here assesses the role of the signaling molecule protein kinase C theta (PKCθ) in the induction of IL-10 expression in CD4(+) T cells. Using wildtype and PKCθ-deficient Tg4 T cell rec...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291537/ https://www.ncbi.nlm.nih.gov/pubmed/28158245 http://dx.doi.org/10.1371/journal.pone.0171547 |