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Protein kinase C theta is required for efficient induction of IL-10-secreting T cells

Secretion of interleukin-10 (IL-10) by CD4(+) T cells is an essential immunoregulatory mechanism. The work presented here assesses the role of the signaling molecule protein kinase C theta (PKCθ) in the induction of IL-10 expression in CD4(+) T cells. Using wildtype and PKCθ-deficient Tg4 T cell rec...

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Detalles Bibliográficos
Autores principales:	Britton, Graham J., Mitchell, Ruth E., Burton, Bronwen R., Wraith, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291537/ https://www.ncbi.nlm.nih.gov/pubmed/28158245 http://dx.doi.org/10.1371/journal.pone.0171547

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