Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint

To preserve genome integrity, the S-phase checkpoint senses damaged DNA or nucleotide depletion and when necessary, arrests replication progression and delays cell division. Previous studies, based on two pol2 mutants have suggested the involvement of DNA polymerase epsilon (Pol ε) in sensing DNA re...

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Detalles Bibliográficos
Autores principales: Dmowski, Michał, Rudzka, Justyna, Campbell, Judith L., Jonczyk, Piotr, Fijałkowska, Iwona J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291541/
https://www.ncbi.nlm.nih.gov/pubmed/28107343
http://dx.doi.org/10.1371/journal.pgen.1006572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291541/
https://www.ncbi.nlm.nih.gov/pubmed/28107343
http://dx.doi.org/10.1371/journal.pgen.1006572

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