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Synthesis and Reactivity of Triazaphenanthrenes

[Image: see text] Pyridonaphthyridines (triazaphenanthrenes) were prepared in 4 steps and in 13–52% overall yield using Negishi cross-couplings between iodopicolines and 2-chloro-pyridylzinc derivatives. After chlorination, Gabriel amination and spontaneous ring-closure, the final aromatization lead...

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Detalles Bibliográficos
Autores principales: Fernandez, Sarah, Ganiek, Maximilian A., Karpacheva, Mariia, Hanusch, Fabian C., Reuter, Stephan, Bein, Thomas, Auras, Florian, Knochel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291649/
https://www.ncbi.nlm.nih.gov/pubmed/27321707
http://dx.doi.org/10.1021/acs.orglett.6b01373