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Single-cell mRNA isoform diversity in the mouse brain

BACKGROUND: Alternative mRNA isoform usage is an important source of protein diversity in mammalian cells. This phenomenon has been extensively studied in bulk tissues, however, it remains unclear how this diversity is reflected in single cells. RESULTS: Here we use long-read sequencing technology c...

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Detalles Bibliográficos
Autores principales: Karlsson, Kasper, Linnarsson, Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291953/
https://www.ncbi.nlm.nih.gov/pubmed/28158971
http://dx.doi.org/10.1186/s12864-017-3528-6