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CD73/NT5E is a target of miR-30a-5p and plays an important role in the pathogenesis of non-small cell lung cancer

BACKGROUND: CD73 (ecto-5′-nucleotidase) is implicated in the development of many types of cancer. CD73 inhibitors are currently being tested in clinical trials for the treatment of cancer. Understanding the molecular and cellular actions of CD73 inhibitors is the key to improving this line of therap...

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Detalles Bibliográficos
Autores principales: Zhu, Jianjie, Zeng, Yuanyuan, Li, Wei, Qin, Hualong, Lei, Zhe, Shen, Dan, Gu, Dongmei, Huang, Jian-an, Liu, Zeyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291990/
https://www.ncbi.nlm.nih.gov/pubmed/28158983
http://dx.doi.org/10.1186/s12943-017-0591-1