Immunogenicity and Cross Protection in Mice Afforded by Pandemic H1N1 Live Attenuated Influenza Vaccine Containing Wild-Type Nucleoprotein

Since conserved viral proteins of influenza virus, such as nucleoprotein (NP) and matrix 1 protein, are the main targets for virus-specific CD8+ cytotoxic T-lymphocytes (CTLs), we hypothesized that introduction of the NP gene of wild-type virus into the genome of vaccine reassortants could lead to b...

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Detalles Bibliográficos
Autores principales: Rekstin, Andrey, Isakova-Sivak, Irina, Petukhova, Galina, Korenkov, Daniil, Losev, Igor, Smolonogina, Tatiana, Tretiak, Tatiana, Donina, Svetlana, Shcherbik, Svetlana, Bousse, Tatiana, Rudenko, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292185/
https://www.ncbi.nlm.nih.gov/pubmed/28210631
http://dx.doi.org/10.1155/2017/9359276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292185/
https://www.ncbi.nlm.nih.gov/pubmed/28210631
http://dx.doi.org/10.1155/2017/9359276

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