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Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets

While recent advances clarified the molecular and cellular modes of action of antiarrhythmic drugs (AADs), their link to suppression of dynamical arrhythmia mechanisms remains only partially understood. The current classifications of AADs (Classes I, III, and IV) rely on blocking peak Na, K and L-ty...

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Detalles Bibliográficos
Autores principales: Karagueuzian, Hrayr S., Pezhouman, Arash, Angelini, Marina, Olcese, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292429/
https://www.ncbi.nlm.nih.gov/pubmed/28220073
http://dx.doi.org/10.3389/fphar.2017.00036