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Defective T-cell control of Epstein–Barr virus infection in multiple sclerosis

Mounting evidence indicates that infection with Epstein–Barr virus (EBV) has a major role in the pathogenesis of multiple sclerosis (MS). Defective elimination of EBV-infected B cells by CD8(+) T cells might cause MS by allowing EBV-infected autoreactive B cells to accumulate in the brain. Here we u...

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Detalles Bibliográficos
Autores principales: Pender, Michael P, Csurhes, Peter A, Burrows, Jacqueline M, Burrows, Scott R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292561/
https://www.ncbi.nlm.nih.gov/pubmed/28197337
http://dx.doi.org/10.1038/cti.2016.87