A Model of Induction of Cerebellar Long-Term Depression Including RKIP Inactivation of Raf and MEK

We report an updated stochastic model of cerebellar Long Term Depression (LTD) with improved realism. Firstly, we verify experimentally that dissociation of Raf kinase inhibitor protein (RKIP) from Mitogen-activated protein kinase kinase (MEK) is required for cerebellar LTD and add this interaction...

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Detalles Bibliográficos
Autores principales: Hepburn, Iain, Jain, Anant, Gangal, Himanshu, Yamamoto, Yukio, Tanaka-Yamamoto, Keiko, De Schutter, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292618/
https://www.ncbi.nlm.nih.gov/pubmed/28220061
http://dx.doi.org/10.3389/fnmol.2017.00019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292618/
https://www.ncbi.nlm.nih.gov/pubmed/28220061
http://dx.doi.org/10.3389/fnmol.2017.00019

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