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Glucose deprivation regulates the progranulin–sortilin axis in PC12 cells

Progranulin (PGRN) is a growth factor implicated in several neurodegenerative diseases, such as frontotemporal lobar degeneration. Despite its important role in the central nervous system (CNS), the mechanisms controlling PGRN expression in the CNS are largely unknown. Recent evidence, however, sugg...

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Detalles Bibliográficos
Autores principales: Kawashima, Ken‐ichi, Ishiuchi, Yuri, Konnai, Miki, Komatsu, Saori, Sato, Hitoshi, Kawaguchi, Hideo, Miyanishi, Nobumitsu, Lamartine, Jérôme, Nishihara, Masugi, Nedachi, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292667/
https://www.ncbi.nlm.nih.gov/pubmed/28174682
http://dx.doi.org/10.1002/2211-5463.12164