Cargando…
Glucose deprivation regulates the progranulin–sortilin axis in PC12 cells
Progranulin (PGRN) is a growth factor implicated in several neurodegenerative diseases, such as frontotemporal lobar degeneration. Despite its important role in the central nervous system (CNS), the mechanisms controlling PGRN expression in the CNS are largely unknown. Recent evidence, however, sugg...
Autores principales: | Kawashima, Ken‐ichi, Ishiuchi, Yuri, Konnai, Miki, Komatsu, Saori, Sato, Hitoshi, Kawaguchi, Hideo, Miyanishi, Nobumitsu, Lamartine, Jérôme, Nishihara, Masugi, Nedachi, Taku |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292667/ https://www.ncbi.nlm.nih.gov/pubmed/28174682 http://dx.doi.org/10.1002/2211-5463.12164 |
Ejemplares similares
-
Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency
por: Lee, Wing C., et al.
Publicado: (2014) -
Progranulin regulates neuronal outgrowth independent of Sortilin
por: Gass, Jennifer, et al.
Publicado: (2012) -
Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin
por: Du, Huan, et al.
Publicado: (2022) -
Subtoxic levels of hydrogen peroxide induce brain-derived neurotrophic factor expression to protect PC12 cells
por: Ogura, Yurina, et al.
Publicado: (2014) -
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
por: Zhou, Xiaolai, et al.
Publicado: (2015)