Proteome and Acetylome Analysis Identifies Novel Pathways and Targets Regulated by Perifosine in Neuroblastoma

Perifosine, an Akt inhibitor, has been shown to be effective in controlling neuroblastoma tumor growth. However, studies indicate that in addition to the ability to inhibit Akt, other mechanisms contribute to perifosine’s anti-tumor activity. To gain insight into perifosine anti-tumor activity in ne...

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Detalles Bibliográficos
Autores principales: Gu, Xiao, Hua, Zhongyan, Dong, Yudi, Zhan, Yue, Zhang, Xiaowen, Tian, Wei, Liu, Zhihui, Thiele, Carol J., Li, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292702/
https://www.ncbi.nlm.nih.gov/pubmed/28165023
http://dx.doi.org/10.1038/srep42062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292702/
https://www.ncbi.nlm.nih.gov/pubmed/28165023
http://dx.doi.org/10.1038/srep42062

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