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Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease

Chronic graft-versus-host disease (cGVHD) is a major complication of hematopoietic stem cell transplantation. Dry eye disease is the prominent ocular sequel of cGVHD and is caused by excessive inflammation and fibrosis in the lacrimal glands. Heavy chain-Hyaluronan/Pentraxin 3 (HC-HA/PTX3) is a comp...

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Detalles Bibliográficos
Autores principales: Ogawa, Yoko, He, Hua, Mukai, Shin, Imada, Toshihiro, Nakamura, Shigeru, Su, Chen-Wei, Mahabole, Megha, Tseng, Scheffer C. G., Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292704/
https://www.ncbi.nlm.nih.gov/pubmed/28165063
http://dx.doi.org/10.1038/srep42195