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Relevance of mortalin to cancer cell stemness and cancer therapy

Mortalin/mtHsp70 is a member of Hsp70 family of proteins. Enriched in a large variety of cancers, it has been shown to contribute to the process of carcinogenesis by multiple ways including inactivation of tumor suppressor p53 protein, deregulation of apoptosis and activation of EMT signaling. In th...

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Detalles Bibliográficos
Autores principales: Yun, Chae-Ok, Bhargava, Priyanshu, Na, Youjin, Lee, Jung-Sun, Ryu, Jihoon, Kaul, Sunil C., Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292728/
https://www.ncbi.nlm.nih.gov/pubmed/28165047
http://dx.doi.org/10.1038/srep42016