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Mitochondrial contribution to lipofuscin formation

Mitochondria have been in the focus of oxidative stress and aging research for decades due to their permanent production of ROS during the oxidative phosphorylation. The hypothesis exists that mitochondria are involved in the formation of lipofuscin, an autofluorescent protein aggregate that accumul...

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Detalles Bibliográficos
Autores principales: König, Jeannette, Ott, Christiane, Hugo, Martín, Jung, Tobias, Bulteau, Anne-Laure, Grune, Tilman, Höhn, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292761/
https://www.ncbi.nlm.nih.gov/pubmed/28160744
http://dx.doi.org/10.1016/j.redox.2017.01.017