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Mitochondrial contribution to lipofuscin formation
Mitochondria have been in the focus of oxidative stress and aging research for decades due to their permanent production of ROS during the oxidative phosphorylation. The hypothesis exists that mitochondria are involved in the formation of lipofuscin, an autofluorescent protein aggregate that accumul...
Autores principales: | König, Jeannette, Ott, Christiane, Hugo, Martín, Jung, Tobias, Bulteau, Anne-Laure, Grune, Tilman, Höhn, Annika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292761/ https://www.ncbi.nlm.nih.gov/pubmed/28160744 http://dx.doi.org/10.1016/j.redox.2017.01.017 |
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