Cargando…

Coenzyme Q(10) partially restores pathological alterations in a macrophage model of Gaucher disease

BACKGROUND: Gaucher disease (GD) is caused by mutations in the GBA1 gene which encodes lysosomal β-glucocerebrosidase (GCase). In GD, partial or complete loss of GCase activity causes the accumulation of the glycolipids glucosylceramide (GlcCer) and glucosylsphingosine in the lysosomes of macrophage...

Descripción completa

Detalles Bibliográficos
Autores principales:	de la Mata, Mario, Cotán, David, Oropesa-Ávila, Manuel, Villanueva-Paz, Marina, de Lavera, Isabel, Álvarez-Córdoba, Mónica, Luzón-Hidalgo, Raquel, Suárez-Rivero, Juan M., Tiscornia, Gustavo, Sánchez-Alcázar, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292786/ https://www.ncbi.nlm.nih.gov/pubmed/28166796 http://dx.doi.org/10.1186/s13023-017-0574-8

Ejemplares similares

Mitochondrial Dysfunction in Lysosomal Storage Disorders
por: de la Mata, Mario, et al.
Publicado: (2016)

Pharmacological Chaperones and Coenzyme Q(10) Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
por: de la Mata, Mario, et al.
Publicado: (2015)

Mitochondrial Dynamics in Mitochondrial Diseases
por: Suárez-Rivero, Juan M., et al.
Publicado: (2016)

Atherosclerosis and Coenzyme Q(10)
por: Suárez-Rivero, Juan M., et al.
Publicado: (2019)

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis
por: Povea-Cabello, Suleva, et al.
Publicado: (2017)

Coenzyme Q(10): Novel Formulations and Medical Trends
por: Pastor-Maldonado, Carmen J., et al.
Publicado: (2020)

Coenzyme Q(10) Analogues: Benefits and Challenges for Therapeutics
por: Suárez-Rivero, Juan M., et al.
Publicado: (2021)

Mitochondrial Myopathy in Follow-up of a Patient With Chronic Fatigue Syndrome
por: Galán, Fernando, et al.
Publicado: (2015)

Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
por: Villanueva-Paz, Marina, et al.
Publicado: (2016)

Stabilization of apoptotic cells: generation of zombie cells
por: Oropesa-Ávila, M, et al.
Publicado: (2014)

Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases
por: Ivanova, Margarita M., et al.
Publicado: (2019)

Induced Pluripotent Stem Cell Modeling of Gaucher’s Disease: What Have We Learned?
por: Santos, Dino Matias, et al.
Publicado: (2017)

Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6
por: Acosta Lopez, Manuel J., et al.
Publicado: (2019)

Metabolic Targets of Coenzyme Q10 in Mitochondria
por: Hidalgo-Gutiérrez, Agustín, et al.
Publicado: (2021)

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging
por: Ben-Meir, Assaf, et al.
Publicado: (2015)

Causes of low muscle coenzyme-Q levels beyond primary coenzyme-Q-deficiency
por: Finsterer, Josef, et al.
Publicado: (2018)

Survival transcriptome in the coenzyme Q(10) deficiency syndrome is acquired by epigenetic modifications: a modelling study for human coenzyme Q(10) deficiencies
por: Fernández-Ayala, Daniel J M, et al.
Publicado: (2013)

Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q(10) Effect on Clinical Improvement
por: Cordero, Mario D., et al.
Publicado: (2012)

Coenzyme Q(10) and Cardiovascular Diseases
por: Gutierrez-Mariscal, Francisco M., et al.
Publicado: (2021)

Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings
por: González-García, Pilar, et al.
Publicado: (2021)

Cell Survival from Chemotherapy Depends on NF-κB Transcriptional Up-Regulation of Coenzyme Q Biosynthesis
por: Brea-Calvo, Gloria, et al.
Publicado: (2009)

Association between genetic variants in the Coenzyme Q(10 )metabolism and Coenzyme Q(10 )status in humans
por: Fischer, Alexandra, et al.
Publicado: (2011)

Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
por: Oropesa-Ávila, M, et al.
Publicado: (2013)

Human Coenzyme Q(10) Deficiency
por: Quinzii, Catarina M., et al.
Publicado: (2006)

Coenzyme Q10: The essential nutrient
por: Saini, Rajiv
Publicado: (2011)

COENZYME Q 10 : A REVIEW
por: Singh, Deependra, et al.
Publicado: (2002)

Coenzyme Q10 and Neurological Diseases
por: Mancuso, Michelangelo, et al.
Publicado: (2009)

Coenzyme Q10 in acute influenza
por: Chase, Maureen, et al.
Publicado: (2018)

The Paradox of Coenzyme Q(10) in Aging
por: Díaz-Casado, M. Elena, et al.
Publicado: (2019)

Coenzyme Q and its role in glaucoma
por: Ahmad, Syed S.
Publicado: (2020)

How plants synthesize coenzyme Q
por: Xu, Jing-Jing, et al.
Publicado: (2022)

Biosynthesis, Deficiency, and Supplementation of Coenzyme Q
por: Staiano, Carmine, et al.
Publicado: (2023)

Bioaccessibility of β-Lactoglobulin Nanoemulsions Containing Coenzyme Q(10): Impact of Droplet Size on the Bioaccessibility of Coenzyme Q(10)
por: Ha, Ho-Kyung, et al.
Publicado: (2018)

Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency
por: Pierrel, Fabien
Publicado: (2017)

The efficacy of coenzyme Q(10) treatment in alleviating the symptoms of primary coenzyme Q(10) deficiency: A systematic review
por: Wang, Ying, et al.
Publicado: (2022)

Gaucher Disease and Gaucher Cells
por: Gözdaşoğlu, Sevgi
Publicado: (2015)

Role of Partial Splenectomy in Gaucher's Disease in Resource Challenged Nations
por: Santanakrishnan, Ramesh, et al.
Publicado: (2023)

The Role of Citicoline and Coenzyme Q10 in Retinal Pathology
por: García-López, Claudia, et al.
Publicado: (2023)

Coenzyme Q10 effects in neurodegenerative disease
por: Spindler, Meredith, et al.
Publicado: (2009)

Coenzyme Q supplementation in pulmonary arterial hypertension
por: Sharp, Jacqueline, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7sdst8dq2l188s87p0hhla88bv