A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis

Massively parallel sequencing technology coupled with saturation mutagenesis has provided new and global insights into gene functions and roles. At a simplistic level, the frequency of mutations within genes can indicate the degree of essentiality. However, this approach neglects to take account of...

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Detalles Bibliográficos
Autores principales: Yang, Zheng Rong, Bullifent, Helen L., Moore, Karen, Paszkiewicz, Konrad, Saint, Richard J., Southern, Stephanie J., Champion, Olivia L., Senior, Nicola J., Sarkar-Tyson, Mitali, Oyston, Petra C. F., Atkins, Timothy P., Titball, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292949/
https://www.ncbi.nlm.nih.gov/pubmed/28165493
http://dx.doi.org/10.1038/srep41923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292949/
https://www.ncbi.nlm.nih.gov/pubmed/28165493
http://dx.doi.org/10.1038/srep41923

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