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Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes

Altered DNA methylation in addiction-related genes may modify the susceptibility to alcohol or drug dependence (AD or ND). We profiled peripheral blood DNA methylation levels of 384 CpGs in promoter regions of 82 addiction-related genes in 256 African Americans (AAs) (117 cases with AD-ND codependen...

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Detalles Bibliográficos
Autores principales: Xu, Hongqin, Wang, Fan, Kranzler, Henry R., Gelernter, Joel, Zhang, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292964/
https://www.ncbi.nlm.nih.gov/pubmed/28165486
http://dx.doi.org/10.1038/srep41816