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Maxadilan-simile expression in Nyssomyia neivai, a sandfly vector in an endemic region of Brazil, and its immunogenicity in patients with American tegumentary leishmaniasis

BACKGROUND: Maxadilan (Max) is a salivary component in the sandfly Lutzomyia longipalpis (Lutz & Neiva 1912), a vector of visceral leishmaniasis. Max has a powerful vasodilatory effect and is a candidate vaccine that has been tested in experimental leishmaniasis. Nyssomyia neivai (Pinto 1926) is...

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Detalles Bibliográficos
Autores principales: Aires, Juliana, Casanova, Claudio, Vernal, Sebastian, Nascimento, Margarida, Rodrigues, Sandra, Lerner, Ethan A, Roselino, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293120/
https://www.ncbi.nlm.nih.gov/pubmed/28177045
http://dx.doi.org/10.1590/0074-02760160351