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Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

BACKGROUND: Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE: Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS: L. braziliensis-GFP was generated using Leishm...

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Detalles Bibliográficos
Autores principales: Bastos, Matheus Silva e, de Souza, Luciana Ângelo, Onofre, Thiago Souza, Silva, Abelardo, de Almeida, Márcia Rogéria, Bressan, Gustavo Costa, Fietto, Juliana Lopes Rangel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293125/
https://www.ncbi.nlm.nih.gov/pubmed/28177050
http://dx.doi.org/10.1590/0074-02760160237