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A Chemoattractant Role for NT-3 in Proprioceptive Axon Guidance

Neurotrophin-3 (NT-3) is required for proprioceptive neuron survival. Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling. TrkC-positive peripheral and central axons from dorsal root gangli...

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Detalles Bibliográficos
Autores principales: Genç, Barış, Özdinler, P. Hande, Mendoza, April E, Erzurumlu, Reha S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529315/
https://www.ncbi.nlm.nih.gov/pubmed/15550985
http://dx.doi.org/10.1371/journal.pbio.0020403