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A Chemoattractant Role for NT-3 in Proprioceptive Axon Guidance
Neurotrophin-3 (NT-3) is required for proprioceptive neuron survival. Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling. TrkC-positive peripheral and central axons from dorsal root gangli...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529315/ https://www.ncbi.nlm.nih.gov/pubmed/15550985 http://dx.doi.org/10.1371/journal.pbio.0020403 |