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Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli

Transcription networks consist of hundreds of transcription factors with thousands of often overlapping target genes. While we can reliably measure gene expression changes, we still understand relatively little why expression changes the way it does. How does a coordinated response emerge in such co...

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Detalles Bibliográficos
Autores principales: Kochanowski, Karl, Gerosa, Luca, Brunner, Simon F, Christodoulou, Dimitris, Nikolaev, Yaroslav V, Sauer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293157/
https://www.ncbi.nlm.nih.gov/pubmed/28049137
http://dx.doi.org/10.15252/msb.20167402