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Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif)

Cycle inhibiting factors (Cifs) are virulence proteins secreted by the type III secretion system of some Gram-negative pathogenic bacteria including Burkholderia pseudomallei. Cif is known to function to deamidate Nedd8, leading to inhibition of Cullin E3 ubiquitin ligases (CRL) and consequently ind...

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Detalles Bibliográficos
Autores principales: Ng, Mei Ying, Wang, Mei, Casey, Patrick J., Gan, Yunn-Hwen, Hagen, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293191/
https://www.ncbi.nlm.nih.gov/pubmed/28166272
http://dx.doi.org/10.1371/journal.pone.0171464