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Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif)
Cycle inhibiting factors (Cifs) are virulence proteins secreted by the type III secretion system of some Gram-negative pathogenic bacteria including Burkholderia pseudomallei. Cif is known to function to deamidate Nedd8, leading to inhibition of Cullin E3 ubiquitin ligases (CRL) and consequently ind...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293191/ https://www.ncbi.nlm.nih.gov/pubmed/28166272 http://dx.doi.org/10.1371/journal.pone.0171464 |