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Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization

Serine/arginine protein kinases (SRPKs) phosphorylate Arg/Ser dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular processes. The existence of a large internal spacer sequence that separates the bipartite kinase catalytic core is a unique structural feature of...

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Detalles Bibliográficos
Autores principales:	Koutroumani, Maria, Papadopoulos, Georgios E., Vlassi, Metaxia, Nikolakaki, Eleni, Giannakouros, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293202/ https://www.ncbi.nlm.nih.gov/pubmed/28166275 http://dx.doi.org/10.1371/journal.pone.0171328

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