Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium

Barrett's metaplasia is the only known morphological precursor to oesophageal adenocarcinoma and is characterized by replacement of stratified squamous epithelium by columnar epithelium. The cell of origin is uncertain and the molecular mechanisms responsible for the change in cellular phenotyp...

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Detalles Bibliográficos
Autores principales: Colleypriest, Benjamin J., Burke, Zoë D., Griffiths, Leonard P., Chen, Yu, Yu, Wei-Yuan, Jover, Ramiro, Bock, Michael, Biddlestone, Leigh, Quinlan, Jonathan M., Ward, Stephen G., Mark Farrant, J., Slack, Jonathan M.W., Tosh, David.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293356/
https://www.ncbi.nlm.nih.gov/pubmed/27875772
http://dx.doi.org/10.1016/j.diff.2016.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293356/
https://www.ncbi.nlm.nih.gov/pubmed/27875772
http://dx.doi.org/10.1016/j.diff.2016.11.001

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