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Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium
Barrett's metaplasia is the only known morphological precursor to oesophageal adenocarcinoma and is characterized by replacement of stratified squamous epithelium by columnar epithelium. The cell of origin is uncertain and the molecular mechanisms responsible for the change in cellular phenotyp...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293356/ https://www.ncbi.nlm.nih.gov/pubmed/27875772 http://dx.doi.org/10.1016/j.diff.2016.11.001 |