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A fully integrated new paradigm for lithium’s mode of action – lithium utilizes latent cellular fail-safe mechanisms
It is proposed that lithium’s therapeutic effects occur indirectly by augmenting a cascade of protective “fail-safe” pathways pre-configured to activate in response to a dangerous low cell [Mg(++)] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. L...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293501/ https://www.ncbi.nlm.nih.gov/pubmed/28203080 http://dx.doi.org/10.2147/NDT.S123612 |